Access to Port Isabel and the surrounding communities is mostly by ground vehicle via either Highway 48 from Brownsville or Highway 100 from Interstate 77. Access to Port Isabel and South Padre Island, from Brownsville and Matamoros, is facilitated by the expansion of highway 48 by the Texas Department of Transportation (TXDOT). This highway is a full four-lane venue from the entry to the Port of Brownsville north to the intersection of Highway 100 in Port Isabel.
Whether you're traveling to or from the Tropical Tip of Texas on business or pleasure:
Brownsville/South Padre Island International Airport Is 22 Miles Away
Mc-Allen Miller International Airport Is 70 Miles Away
Port Isabel Cameron County Private Airport Is 10 Miles Away